Troponin Variants as Markers of Skeletal Muscle Health and Diseases
Ca2+-regulated contractility is a key determinant of the quality of muscles.The sarcomeric myofilament proteins are essential players in the contraction of striated muscles.The troponin complex in the actin thin filaments plays a central role in the Ca2+-regulation of muscle contraction and relaxation.Among the three subunits of troponin, the Ca2+-